Rotary Evaporators’ Extraction Method
Rotary evaporators extract and concentrate substances from mixtures by heating and evaporating sample materials according to the different boiling points of substances within mixtures. The basic principle of rotary evaporators is the vacuum distillation of the distillation flask under continuous rotation. Many people still wonder the very specific details of rotary evaporators’ extraction method, which will be introduced next.
The extraction process starts with the water oil bath. Firstly, set up the heating temperature of the water oil bath, which are supposed to be same as the boiling point of the components to be extracted. Due to the boiling points will be reduced with decreasing pressure, the components’s boiling points will lower than that under normal pressure. After the components to be extracted get evaporated successfully, it will be transferred into the condenser where gas-phase substance will be cooled down and becomes liquid-phase. The liquid-phase substance is easier to be collected than the gas-phase substance. Finally, after the gas-phase becomes liquid-phase, the extracted substance will go into the receiving flask, which is easy for users to collect.
The Improvement of Rotary Evaporators’ Extraction Method
The rotary evaporator method, liquid-liquid extraction can extract substances efficiently, but it still has some disadvantages. So people use solid phase extraction (SPE), which was used for the formulation of several radiopharmaceuticals for a better use. Due to its high efficiency, reliability, and low consumption of reagents, it has replaced traditional liquid-liquid extraction in many fields and has become an effective means for sample preparation.